Pissavini M, Tricaud C, Wiener G,
Lauer A, Contier M, Kolbe L, Trullás Cabanas C, Boyer F, Meredith E, de
Lapuente J, Dietrich E, Matts PJ. Validation of a new in vitro sun protection
factor (SPF) method to include a wide range of sunscreen product emulsion
types. Int. J. Cosmet. Sci. 2020; 42: 421-428 https://dx.doi.org/10.1111/ics.12625
Ruvolo E, Aeschliman L, Cole C. Evaluation of
sunscreen efficacy over time and re-application using hybrid diffuse
reflectance spectroscopy. Photodermatol. Photoimmunol. Photomed. 2020; 36 (3): 192-199
https://dx.doi.org/10.1111/phpp.12535
Throm CM, Wiora G, Reble C, Schleusener J,
Schanzer S, Karrer H, Kolbe L, Khazaka G, Meinke MC, Lademann J. In vivo sun
protection factor and UVA protection factor determination using (hybrid)
diffuse reflectance spectroscopy and a multi-lambda-LED light source. J.
Biophotonics 2020; e202000348 https://doi.org/10.1002/jbio.202000348
Mann T, Eggers K, Rippke F, Tesch M, Buerger A,
Darvin ME, Schanzer S, Meinke MC, Lademann J, Kolbe L. High-energy visible
light at ambient doses and intensities induces oxidative stress of skin -
Protective effects of the antioxidant and Nrf2 inducer Licochalcone A in vitro
and in vivo. Photodermatol. Photoimmunol. Photomed. 2020; 36 (2): 135-144 https://doi.org/10.1111/phpp.12523
Hebert
AA, Rippke F, Weber TM, Nicol NH. Efficacy of nonprescription moisturizers for atopic dermatitis: An
updated review of clinical evidence. Am. J. Clin. Derm. 2020; 21: 641–655 https://doi.org/10.1007/s40257-020-00529-9
Philipp-Dormston WG, Vila Echagüe A, Pérez
Damonte SH, Riedel J, Filbry A, Warnke K, Lofrano C, Roggenkamp D, Nippel G.
Thiamidol containing treatment regimens in facial hyperpigmentation: an international
multi-center approach consisting of a double-blind, controlled, split-face study
and of an open label, real-world study. Int. J. Cosmet. Sci. 2020; 42: 377-387 https://dx.doi.org/10.1111/ics.12626
Srour J, Bengel J, Linden T, Jovanovic Z,
Roggenkamp D, Reinholz M, Rothenberger C, Neufang G, Wollenberg A. Efficacy of
a skin care cream with TRPV1 inhibitor 4-t-butylcyclohexanol in the topical
therapy of perioral dermatitis. J. Cosmet. Dermatol. 2020; 19 (6): 1409-1414 https://doi.org/10.1111/jocd.13175
Kuhn A, Batzer J, Willenberg M,
Kristof S, Bussmann T, Weise J, Drescher P, Van Geloven AM, Buerger A,
Gallinger J. Novel cleansing formulations containing Hyaluronic acid
efficiently cleanse while improving skin hydration as optimal preparation for
skin care application. Poster, 29th EADV Congress Virtual 2020
Laudien M, Siefken W, Baericke L, Willenberg M,
Seidel J, Reuter H, Oberst S, Burkhardt T, Rippke F, Gallinger J, Bussmann T.
Licochalcone A inhibits C. acnes biofilm associated lipase activity and
penetrates the sebaceous glands. Poster, 29th EADV Congress Virtual 2020
Mann T, Welge V, Weise J, Roggenkamp
D, Kolbe L Efficacy of Thiamidol, Niacinamide, Tranexamic acid, Cysteamine,
Azelaic acid on melanin production in vitro. Poster, 29th EADV
Congress Virtual 2020
Roggenkamp D, Fürstenau M, Kausch M,
Sammain A, Kolbe L. 24 weeks long-term efficacy and tolerability of a skin care
regimen with Thiamidol in patients with moderate to severe facial
hyperpigmentation. Poster, 29th EADV Congress Virtual 2020
Schmidt L, van Geloven A, Harbig S,
Fürstenau M, Muhr G, Dippe R, Warnke K. Closing a need gap – Effective anti-age
care targeting age spots for more skin evenness. Poster, 29th EADV
Congress Virtual 2020
Warnke K, Harbig S, Fürstenau M,
Dippe R, Kristof S, Weise J, van Geloven A. Advanced anti-aging serum with
multifunctional benefits targeting urban skin needs. Poster, 29th EADV
Congress Virtual 2020
Worthmann A, Scherdin U, Gallinger
J. An anti-itch spray formulation significantly reduces itch associated with
various skin conditions. Poster, 29th EADV Congress Virtual 2020
Laudien M, Altgilbers S, Kuhn A,
Higuera S, Natsch A, Filbry A, Schmidt L, Weise J2, Rippke F, Gallinger J.
Shifting the perfume paradigm: A novel allergen-depleted fragrance composition
provides anti-inflammatory effects in vitro and soothes xerotic skin in vivo to
enhance patients’ treatment adherence. Poster, 29th EADV Congress
Virtual 2020
Weber TM , Arrowitz CE, Scherdin U,
Schoelermann AM, Filbry A, Sammain A. A moisturizing Ointment Body Spray to
help alleviate dry skin symptoms associated with atopic eczema, psoriasis and
xerosis cutis. Poster, 29th EADV Congress Virtual 2020
Weber TM , Arrowitz CE, Scherdin U,
Schoelermann AM, Filbry A, Sammain A. Efficacy of an Ointment Body Spray (OBS)
to improve the appearance of dry, ashy skin and alleviate moderate to severe
dryness on the heel. Poster, 29th EADV Congress Virtual 2020
Hoefner C, Muhr C, Horder H, Wiesner M, Wittmann
K, Lukaszyk D, Radeloff K, Winnefeld M, Becker M, Blunk T, Bauer-Kreisel P.
Human adipose-derived mesenchymal stromal/stem cell spheroids possess high adipogenic
capacity and acquire an adipose tissue-like extracellular matrix pattern.
Tissue Eng. Part A. 2020; 26 (15-16): 1-12 https://dx.doi.org/10.1089/ten.tea.2019.0206.
Holzscheck N, Söhle J, Schläger T, Falckenhayn
C, Grönniger E, Kolbe L, Wenck H,
Terstegen L, Kaderali L, Winnefeld M, Gorges K. Concomitant DNA methylation
and transcriptome signatures define epidermal responses to acute solar UV
radiation. Sci. Rep. 2020; 10: 12918 https://doi.org/10.1038/s41598-020-69683-8
Holzscheck N, Söhle J, Kristof B,
Groenniger E, Gallinat S, Wenck H, Winnefeld M. Falckenhayn C, Kaderali L.
Multi-omics network analysis reveals distinct stages in the human aging
progression in epidermal tissue. Aging 2020; 12 (12): 12393-12409
Holzscheck N, Söhle J, Schläger T,
Roggenkamp D, Grönniger E, Falckenhayn C. Repetitive irradiation with
sub-erythemal UV dose induces changes in human
epidermis on three cellular levels: DNA structure, epigenetic DNA methylation
and gene expression. Poster, 29th EADV Congress Virtual 2020
Ahlers JMD, Rodriguez M, Kaufmann R,
Lyko F, Groenniger E. Modulation of chromatin accessibility to restore skin
plasticity as an anti-aging strategy. Poster, Keystone eSymposium Tissue
Plasticity: Preservation and Alteration of Cellular Identity 2020
Ahle CM, Stødkilde K, Afshar M,
Poehlein A, Ogilvie LA, Söderquist B, Hüpeden J, Brüggemann H. Staphylococcus
saccharolyticus: an overlooked human skin colonizer. Microorganisms 2020; 8:
1105 https://doi.org/10.3390/microorganisms8081105
Witte M, Jaspers S, Wenck H,
Rübhausen M, Fischer F. Noise reduction and quantification of fiber orientations
in greyscale images. PLoS One 2020; 15 (1): e0227534 https://dx.doi.org/10.1371/journal.pone.0227534
Witte M, Jaspers S, Wenck H, Rübhausen M,
Fischer F. General method for classification of fiber families in fiber‑reinforced materials: application to in‑vivo human skin images. Sci. Rep. 2020; 10: 10888 https://doi.org/10.1038/s41598-020-67632-z
Zieger M, Kaatz M, Springer S,
Riesenberg S, Wuttig A, Kanka M, Stanca S, Reble C, Khazaka G, Sieg R, De
Gregorio M, Sattler M, Fischer F. Multi-wavelength, handheld laser speckle
imaging for skin evaluation. Skin Res. Technol. 2020; 00: 1-8 https://doi.org/10.1111/srt.12959
Kern C, Speck U, Riesenberg R, Reble
C, Khazaka G, Zieger M, Kaatz M, De Gregorio M, Fischer F. Mobile snapshot
hyperspectral imaging device for skin evaluation using diffractive optical
elements. Skin Res. Technol. 2020; 00: 1-10 https://doi.org/10.1111/srt.12991
Glier TE, Betke M, Witte M, Matsuyama T,
Westphal L, Grimm-Lebsanft B, Biebl, F, Akinsinde L, Fischer F, Rübhausen M:
Electrical and network properties of flexible silver-nanowire composite
electrodes under mechanical strain. Nanoscale 2020; 12: 23831-23837 https://doi.org/10.1039/D0NR05734G
Wilm A, Norinder U, Agea MI, de Bruyn Kops C,
Stork C, Kühnl J, Kirchmair J. Skin Doctor CP: Conformal prediction of the skin sensitization potential
of small organic molecules. Chem. Res. Toxicol. 2020 https://dx.doi.org/10.1021/acs.chemrestox.0c00253?ref=pdf
Eilstein J, Grégoire S, Fabre A,
Arbey E, Géniès C, Duplan H, Rothe H, Ellison C, Cubberley R, Schepky A, Lange
D, Klaric M, Hewitt NJ, Jacques-Jamin C. Use of human liver and EpiSkin™ S9 subcellular
fractions as a screening assays to compare the in vitro hepatic and dermal metabolism
of 47 cosmetics-relevant chemicals. J. Appl. Toxicol. 2020; 40 (3): 416-433 https://doi.org/10.1002/jat.3914
Géniès C, Jacques-Jamin C, Duplan H, Rothe H,
Ellison C, Cubberley R, Schepky A, Lange D, Klaric M, Hewitt NJ, Grégoire S,
Arbey E, Fabre A, Eilstein J. Comparison of the metabolism of 10 cosmetics-relevant
chemicals in EpiSkin™ S9 subcellular fractions and in vitro human skin explants.
J. Appl. Toxicol. 2020; 40 (2): 313-326 https://doi.org/10.1002/jat.3905
Ellison CA, Tankersley KO, Obringer CM, Carr GJ,
Manwaring J, Rothe H, Duplan H, Géniès C, Grégoire S, Hewitt NJ, Jacques-Jamin C, Klaric M,
Lange D, Rolaki A, Schepky A. Partition coefficient and diffusion coefficient
determinations of 50 compounds in human intact skin, isolated skin layers and
isolated stratum corneum lipids. Toxicol. in Vitro 2020; 69: 104990 https://doi.org/10.1016/j.tiv.2020.104990
Hewitt NJ, Grégoire S, Cubberley R, Duplan H,
Eilstein J, Ellison C, Lester C, Fabian E, Fernandez J, Géniès C, Jacques-Jamin
C, Klaric M, Rothe H, Sorrell I, Lange D, Schepky A. Measurement of the
penetration of 56 cosmetic relevant chemicals into and through human skin using
a standardized protocol. J. Appl. Toxicol. 2020; 40: 403–415. https://doi.org/10.1002/jat.3913
Gilmour N, Kern PS, Alepee N, Boisleve F, Bury
D, Clouet F, Hirota M, Hoffmann S, Kühnl
J, Lalko JF, Mewes K, Miyazawa M, Nishida H, Osmani A, Petersohn D, Sekine S,
van Vliet E, Klaric M. Development of a next generation risk assessment
framework for the evaluation of skin sensitisation of cosmetic ingredients.
Regul. Toxicol. Pharmacol. 2020; 116: 104721 https://doi.org/10.1016/j.yrtph.2020.104721
Marx U, Akabane T, Andersson TB, Baker E,
Beilmann M, Beken S, Brendler-Schwaab S, Cirit M, David R, Dehne E-M, Durieux
I, Ewart L, Fitzpatrick SC, Frey O,
Fuchs F, Griffith LG, Hamilton GA, Hartung T, Hoeng J, Hogberg H, Hughes
DJ, Ingber DE, Iskandar A, Kanamori T,
Kojima H, Kuehnl J, Leist M, Li B, Loskill P, Mendrick DL, Neumann T, Pallocca
G, Rusyn I, Smirnova L, Steger-Hartmann T, Tagle DA, Tonevitsky A, Tsyb S,
Trapecar M, van de Water B, van den Eijnden-van Raaij J, Vulto P, Watanabe K,
Wolf A, Zhou X, Roth A. Biology-inspired microphysiological systems to advance
patient benefit and animal welfare in drug development. Altrex 2020; 37 (3):
365-394 https://doi.org/https://doi.org/10.14573/altex.2001241
Kluxen FM, Grégoire S, Schepky A, Hewitt NJ,
Klaric M, Domoradzki JY. Response to “OECD 428 in vitro dermal absorption mass
balance performance based on our in-house database of pesticide studies”.
Regul. Toxicol. Pharmacol. 2020; 115: 104707 https://doi.org/10.1016/j.yrtph.2020.104707
Kühnl J, Brandmair K, Tao TP,Gerlach S,
Müller-Vieira U, Lange D; Marx U, Schepky A, Hewitt N, Maschmeyer I. Use of a
microphysiological system integrating skin and liver models to investigate
effects of different exposure scenarios on the metabolic fate of chemicals and
corresponding tissue responses. Oral Presentation, TEDD Virtual Conference 2020
https://doi.org/10.14573/altex.2012151
Hack CE, Efremenko AY, Pendse SN, Ellison CA,
Najjar A, Hewitt N, Schepky A, Clewell HJ. Physiologically based
pharmacokinetic modeling software. In: Fisher JW, Gearhart JM, Lin Z (Edt).
Physiologically Based Pharmacokinetic (PBPK) Modeling. Academic Press 2020:
81-125
Kuhlmann M, Fliss P, Freese R, Heiermann A, Nosko A, Klensang K, Rauscher C, Wolber R. Local tolerability and clinical performance of a wound care routine concept (medical devices) in the treatment of minor superficial wounds. ePoster, EWMA (European Wound Management Association) conference, November 2020
Kruenholz S, Klensang K, Luettke J, Wilhelm D, Drescher T, Hartkopf C, Kuhlmann M. Local tolerability, therapeutic benefit, and acceptance of a heat patch in the treatment of back pain. ePoster. German Pain Congress 2020; Schmerz 34, 25–103 (p 79, PO058), 2020. https://doi.org/10.1007/s00482-020-00499-1
2019
Mellem D, Fischer F, Jaspers S, Wenck H,
Rübhausen M
Mitochondrial morphologies driven by energy-consuming cell sites
in a spatially
and time-resolved quality model. J. Comput. Biol. 2019, 26 (1):
76-85
Ito
S, Kolbe L, Weets G, Wakamatsu K
Visible light accelerates the ultraviolet A-induced degradation of
eumelanin
and pheomelanin. Pigm. Cell Melanoma Res. 2019, 32 (3): 441-447
Kolbe
L, Pissavini M, Tricaud C, Trullás Cabanas C, Dietrich E, Matts PJ
Anti-inflammatory / anti-oxidant activity of ingredients of
sunscreen products?
Implications for SPF. Int. J. Cosmet. Sci. 2019, 41: 320–324
Arrowitz C, Schoelermann AM, Mann T, Jiang
LI, Weber T, Kolbe L
Effective tyrosinase inhibition by thiamidol results in
significant improvement
of mild to moderate melasma. J. Invest. Dermatol. 2019, 139: 1691-1698
Rippke F, Berardesca E, Weber TM. pH-Wert und mikrobielle
Infektionen. Karger Kompass Dermatol. 2019, 7: 62-67
Schepky A,
Coecke A, Jacques Jamin C, Kuehnl J. In vitro static and dynamic skin
metabolism methods and strategies to address the safety assessment of topically
applied chemicals. Presentation, SOT, San Antonio, USA, March 11-15, 2019
Ellison C. Internal
TTC: Where are we today? What is possible for the near future? Presentation, SCCS
Workshop Brussels, Belgium, February 27, 2019
Zöllner D,
Filbry A, Scherdin U, Harbig S, Rippke F, Schneider G. Busting a modern myth:
Ethanol at a concentration of 10% is very well tolerated in skin care
formulations even by sensitive skin sufferers – Results of 6 independent in vivo studies. Poster, 24th
World Congress of Dermatology, Milano, Italy, 2019
Keyhanian
S, Warnke K, Buerger A, Klensang K, De Kleijn S. Efficacy of a cosmetic
formulation containing Licochalcone A, Salicylic Acid, Decanediol and
sebum-regulating technology with L-Carnitine in subjects with acne lesions. Poster,
24th World Congress of Dermatology, Milano, Italy, 2019
Van Geloven
A, Nizet J, Koop U, Warnke K, Conzelmann S. Formulations containing a
combination of Magnolia Bark Extract, Oligopeptides and Hyaluronic Acid
significantly reduce jowling in ageing skin. Poster, 24th World Congress
of Dermatology, Milano, Italy, 2019
Van Geloven
A, Djamil J, Fürstenau M, Harbig S, Warnke K. Formulations containing a
combination of AHA, Saponin and Hyaluronic Acid significantly improve blemishes
and wrinkles in subjects with ageing skin and acne tarda. Poster, 24th
World Congress of Dermatology, Milano, Italy, 2019
Mann T, Eggers K, Kolbe L
Effective photoprotection against UV- and VIS-induced oxidative
stress by
active ingredients requires Nrf2-induction. Poster, 24th World Congress of
Dermatology, Milano, Italy, 2019
Mann T, Wensorra U, Batzer J, Kolbe L
Effective treatment of post-inflammatory hyperpigmentation (PIH)
with the
tyrosinase inhibitor Thiamidol. Poster, 28th EADV Congress, Madrid, Spain,
2019
Worthmann A, Sperling G, Holtzmann U, Rippke
F, Grönniger E, Roggenkamp D,
Neufang
G, Lofrano C, Perez Damonte S, Vila Echagüe A
Efficacy and tolerability of a skin care regimen with Thiamidol in
patients
with facial hyperpigmentation. Poster, 28th EADV Congress, Madrid, Spain,
2019
Roggenkamp
D, Neufang G, Pillay A, Zoric I, Kausch M, Dlova NC
A skin care regimen with Thiamidol effectively reduces
post-inflammatory
hyperpigmentation in patients with resolved acne. Poster, 28th EADV Congress,
Madrid, Spain, 2019
Kristof S, Holtzmann U, Harbig S, Jung KA,
Geloven AM, Warnke K,
Rippke
R, Groenniger E
A new face care formulation containing 10% Vitamin C and
Licochalcone A
provides a persistent and profound anti-oxidative capacity ex vivo
and beneficial
anti-ageing effects in vivo. Poster, 28th EADV Congress, Madrid, Spain,
2019
Keyhanian
S, Groenniger E, Sperling G
Anti-inflammatory and anti-oxidative properties of Licochalcone A
from
Glycyrrhiza inflata compared to Niacinamide in vitro. Poster, 28th EADV Congress,
Madrid, Spain, 2019
Marcheggiani
F, Cirilli I, Orlando P, Silvestri S, Vogelsang A, Knott A, Blatt T,
Weise
JM, Tiano L
Modulation of Coenzyme Q10 content and oxidative status in human
dermal fibroblasts using HMG-CoA reductase inhibitor over a broad
range
of concentrations. From mitohormesis to mitochondrial dysfunction
and
accelerated aging. Aging (Albany NY) 2019, 11(9): 2565-2582
Holzscheck
N, Falckenhayn C, Söhle J, Kristof B, Gallinat S, Wenck H,
Kaderali
L, Winnefeld M
Multi-omics network analysis reveals age-associated clusters in
human epidermal
tissue. Poster, 27th International conference on Intelligent Systems for Molecular
Biology / 18th European Conference on Computational Biology (ISMB/ECCB),
Basel, Switzerland, 2019
Volz A-C, Omengo B, Gehrke S, Kluger PJ
Comparing the use of differentiated adipose-derived stem cells and
mature
adipocytes to model adipose tissue in vitro. Differentiation 2019, 110:
19-28
Altgilbers
S, Holtzmann U, Rippke F, Filbry A, Conzelmann S, Weber TM, Vietzke JP,
Burkhardt T, Roggenkamp D, Groenniger, E
Enhancement of skin barrier function on a cellular and phenotypic
level:
Integrative effects of a novel multi-functional moisturizer.
Poster, 24th World Congress of Dermatology, Milano, Italy, 2019
Kuhn
A, Wessel S, Behm P, Heinecke S, Hillemann L, Gallinger J
In depth hydration efficacy by a moisturizer containing Urea and
other NMFs
determined by Near-Infrared Confocal Spectroscopic Imaging (KOSIM
IR).
Poster, 28th EADV Congress, Madrid, Spain, 2019
Sulzberger M, Sperling G, Worthmann AC,
Rauscher C, Gallinger J,
Rippke
F, Groenniger E
A novel multi-functional anti-pruritus approach in vitro.
Poster, 28th EADV Congress, Madrid, Spain, 2019
Kuhn
A, Schornstein T, Harbig S, Warnke K, van Geloven A, Dippe R
2D moisture map visualization of fast facial hydration
improvement.
Poster, 28th EADV Congress, Madrid, Spain, 2019
Arrowitz
CE, Jiang LI, Hino PD, Babcock MJ, Weber TM
A Comparison of efficacy among therapeutic moisturizing creams.
Poster, 39th Fall Clinical Dermatology Conference, Las Vegas, NV, USA, 2019
Wilm
A, Stork C, Bauer C, Schepky A, Kühnl J, Kirchmair J
Skin doctor: machine learning models for skin sensitization
prediction
that provide estimates and indicators of prediction reliability.
Int. J. Mol. Sci. 2019, 20: 4833
Kluxen
FM, Grégoire S, Schepky A, Hewitt NJ, Klaric M, Domoradzki JY,
Felkers E, Fernandes J, Fisher P, McEuen SF,
Parr-Dobrzanski R, Wiemann C
Dermal absorption study OECD TG 428 mass balance recommendations
based
on the EFSA database. Regul. Toxicol. Pharmacol. 2019, 108: 104475
Alépée
N, Adriaens E, Abo T, Bagley D, Desprez B, Hibatallah J, Mewes K,
Pfannenbecker
U, Sala À, Van Rompay AR, Verstraelen S, McNamee P
Development of a defined approach for eye irritation or serious
eye damage
for neat liquids based on cosmetics Europe analysis of in vitro
RhCE and BCOP
test methods. Toxicol. In Vitro 2019, 59:100-114
Alépée
N, Adriaens E, Abo T, Bagley D, Desprez B, Hibatallah J, Mewes K,
Pfannenbecker
U, Sala À, Van Rompay AR, Verstraelen S, McNamee P
Development of a defined approach for eye irritation or serious
eye damage
for liquids, neat and in dilution, based on cosmetics Europe
analysis of in vitro
STE and BCOP test methods. Toxicol. In Vitro 2019, 57: 154-163
Grégoire
S, Cubberley R, Duplan H, Eilstein J, Hewitt NJ, Jacques-Jamin C,
Genies
C, Klaric M, Rothe H, Ellison C, Fernandez J, Schepky A
Use of a Simple in vitro test to assess loss of chemical due to
volatility
during an in vitro human skin absorption study. Skin Pharmacol.
Physiol. 2019,
32 (3): 117-124
Ellison
CA, Blackburn KL, Carmichael PL, Clewell HJ 3rd, Cronin MTD, Desprez B,
Escher
SE, Ferguson SS, Grégoire S, Hewitt NJ, Hollnagel HM, Klaric M, Patel A,
Salhi
S, Schepky A, Schmitt BG, Wambaugh JF, Worth A
Challenges in working towards an internal threshold of
toxicological concern
(iTTC) for use in the safety assessment of cosmetics: Discussions
from the
Cosmetics Europe iTTC Working Group workshop. Regul. Toxicol.
Pharmacol.
2019, 103: 63-72
Géniès C, Jamin EL, Debrauwer L, Zalko D,
Person EN, Eilstein J, Grégoire S,
Schepky
A, Lange D, Ellison C, Roe A, Salhi S, Cubberley R, Hewitt NJ, Rothe H,
Klaric
M, Duplan H, Jacques-Jamin C
Comparison of the metabolism of 10 chemicals in human and pig skin
explants.
J. Appl. Toxicol. 2019, 39(2): 385-397
Mastrangeli M, Millet S, ORCHID partners
(Kuehnl J), van den Eijnden-van Raaij J
Organ-on-Chip In Development: Towards a roadmap for
Organs-on-Chip.
Preprints 4 March 2019
Schepky A, Bernau M, Duplan H, Eilstein J,
Ellison C, Fabian E, Genies C,
Grégoire
S, Hewitt N, Jacques-Jamin C, Lester L, Salhi S, Sorrell I, Klaric M
Cosmetics Europe’s non-animal strategy: toxicokinetics for
systemic toxicity
assessment. Presentation, BTS, Cambridge, UK, April 15-17, 2019
Misery
L, Santerre A, Batardière A, Hornez N, Nedelec AS, Le Caër F,
Bourgeois
P, Huet F, Neufang G
Real-life study of anti-itching effects of a cream containing
menthoxypropanediol, a TRPM8 agonist, in atopic dermatitis
patients.
J. Eur. Acad. Dermatol. Venereol. 2019, 33
(2): e67-e69
Pereira
MP, Agelopoulos K, Köllner J, Neufang G, Schmelz M
Selective nerve fibre activation in patients with generalized
chronic pruritus:
hint for central sensitization? Acta Derm. Venereol. 2019, 99:
1009-1015
Kuhlmann
M, Wigger-Alberti W, v. Mackensen Y, Ebbinghaus M, Williams R,
Krause-Kyora
F, Wolber R
Wound healing characteristics of a novel wound healing ointment in
an
abrasive wound model: A randomised, intra-individual clinical
investigation.
Wound Med. 2019, 24: 24-32
Kruenholz S, Klensang K, Kuhlmann M, Lappe S, Wolber R. Non-interventional study on the local tolerability, efficacy and acceptability of a medicated plaster with salicylic acid in the treatment of warts. Oral Presentation, 23rd FIP World Congress of Podiatry, Miami, USA 2019
2018
Mann T, Scherner C, Röhm K-H, Kolbe L.
Structure-activity relationships of thiazolyl resorcinols, potent and selective
inhibitors of human tyrosinase. Int. J. Mol. Sci. 2018, 19: 690
Mann T, Gerwat W, Batzer J, Eggers K, Scherner
C, Wenck H, Stäb F, Hearing VJ, Röhm K-H, Kolbe L. Inhibition of human
tyrosinase requires molecular motifs distinctively different from mushroom
tyrosinase. J. Invest. Dermatol. 2018, 138: 1601-1608
Mann T, Gerwat W, Wenck H, Roehm KH, Kolbe L.
Isobutylamido thiazolyl resorcinol – a highly effective inhibitor of human
tyrosinase. Poster, 27th EADV Congress, Paris, France 2018
Roggenkamp D, Riedel J, Muhr G-M, Warnke K,
Kolbe L, Filbry A. Efficacy of skin care formulations with Thiamidol in
reducing facial hyperpigmentation. Poster, 27th EADV Congress, Paris, France
2018
Eggers K, Mann T, Kolbe L. Antioxidants for
effective photoprotection against high energy visible light. Poster, 27th EADV
Congress, Paris, France 2018
Ladewig S, Mann T, Kolbe L, Weise J.
Licochalcone A protects from reactive oxygen species and matrix
metalloproteinase-1 expression induced by high-energy visiblelight irradiation
in vitro. Poster, 27th EADV Congress, Paris, France 2018
Batzer J, Eggers K, Kolbe L, Weise J. Assessment
of hazard potential of high-energy visible light from electronic devices for
the skin. Poster, 27th EADV Congress, Paris, France 2018
Pissavini M, Tricaud C, Wiener G, Lauer A,
Contier M, Kolbe L, Trullas Cabanas C, Boyer F, Nollent V, Meredith E, Dietrich
E, Matts PJ. Validation of an in vitro sun protection factor (SPF) method in
blinded ring-testing. Int. J. Cosmet. Sci. 2018, 40, 263–268
Bielfeldt S, Klette E, Rohr M, Herzog B,
Grumelard J, Hanay C, Heinrich U, Hansen P, Kockotth D, Lademann J,
Mendrok-Edinger C, Peters,k, Rudolph T, Schläger T, Tronnier H, Wiechers S, Zastrow L, Pflücker F.
Multicenter methodology comparison of the FDA and ISO standard for measurement
of in vitro UVA protection of sunscreen products. J. Photochem. Photobiol. B:
Biol. 2018, 189: 185-192
Rodríguez-Paredes M, Bormann F, Raddatz G, Gutekunst
J, Lucena-Porcel C, Köhler F, Wurzer E,
Schmidt K, Gallinat S, Wenck H, Röwert-Huber J, Denisova E, Feuerbach L, Park J, Brors B, Herpel E, Nindl I, Hofmann
TG, Winnefeld M, Lyko F. Methylation profiling identifies two subclasses of
squamous cell carcinoma related to distinct cells of origin. Nature Commun.
2018, 9: 577
Madsen JGS, Rauch A, Van Hauwaert EL, Schmidt
SF, Winnefeld M, Mandrup S. Integrated analysis of motif activity and gene
expression changes of transcription factors. Genome Res. 2018, 28: 243–255
Bobrov E, Georgievskaya A, Kiselev K,
Sevastopolsky A, Zhavoronkov A, Gurov S, Rudakov K, del Pilar Bonilla Tobar M,
Jaspers S, Clemann C. PhotoAgeClock: deep learning algorithms for development
of non-invasive visual biomarkers of aging. Aging 2018, 10 (11): 3249-3259
Gan J, Wilbert A, Thormählen T, Drescher P,
Hagens R. Multi-view photometric stereo using surface deformation. Visual
Computer 2018, 34 (11): 1551-1561
Blatt T.New results: Q10 and creatine. Cossma 2018: 15-18
Vogelsang A, Krüger A, Sperling G, Batzer J,
Burkhardt T, Grönniger E, Wenck H, Blatt T, Weise JM. Enhancing the anti-aging effects of Coenzyme Q10 by antioxidants and
energy metabolites. Poster, 9th Conference of the International
Coenzyme Q10 Association, New York, USA 2018.
Huet F, Bataille A, Cheret J, Neufang G, De
Kleijn S, Roggenkamp D, Lebonvallet N,
Misery L, Christelle I. Étude in vitro de l’effet du menthoxypropanédiol
sur le prurit au cours de la dermatite atopique : rôle du récepteur TRPM-8
(abstr.). Ann. Derm. Venereol. 2018, 145 (12) Suppl.: S122
Worthmann A, Sperling G, Holtzmann U, Rippke F,
Grönniger E. Polidocanol inhibits the release of thymic stromal lymphopoietin
(TSLP) in human keratinocytes in vitro. Poster, 27th EADV Congress, Paris,
France 2018
Rippke F, Berardesca E, Weber TM. pH and
microbial infections. Curr. Probl. Dermatol. 2018, 54: 87-94
Welge V, Sulzberger M, Worthmann A, Holtzmann U,
Sperling G, Rippke F, Filbry A, Kuhn A, Gallinger J, Grönniger E. A novel body
moisturizer with effective pH buffer system and Dexpanthenol protects the skin
against environmental triggers in vitro, ex vivo and in vivo. Poster, 27th EADV
Congress, Paris, France 2018
Angelova-Fischer I, Rippke F, Richter D, Filbry
A, Arrowitz C, Weber T, Fischer T, Zillikens D. Stand-alone emollient treatment
reduces flares after discontinuation of topical steroid treatment in atopic
dermatitis: a double-blind, randomized, vehicle-controlled, left-right
comparison study. Acta Derm. Venereol. 2018, 98: 517-523
Weber TM, Arrowitz CE, Jiang LI, Qian K, Filbry
A. Efficacy of an ointment body spray to improve the appearance of dry, ashy skin
and alleviate moderate to severe dryness on the heel. Poster, Fall Clinical
Dermatology Conference, Las Vegas, USA 2018
Weber TM, Arrowitz CE, Scherdin U, Schoelermann
AM, Filbry A. A moisturizing spray ointment to help alleviate dry skin symptoms
associated with atopic eczema, psoriasis, and xerosis. Poster, Fall Clinical
Dermatology Conference, Las Vegas, USA 2018
Wilm A, Kühnl J, Kirchmair J. Computational
approaches for skin sensitization prediction. Crit. Rev. Toxicol. 2018, 48 (9):
738-760
Desprez B, Dent M, Keller D, Klaric M, Ouédraogo G, Cubberley R, Duplan H, Eilstein J, Ellison C, Grégoire S, Hewitt
N, Jacques-Jamin C, Lange D, Roe A, Rothe H, Blaauboer B, Schepky A, Mahony C. A
strategy for systemic toxicity assessment based on non-animal approaches: The
cosmetic Europe Long Range Science Strategy programme. Toxicol. in Vitro 2018,
50: 137-146
Hoffmann S, Kleinstreuer N, Alepee N, Allen D,
Apie AM, Ashikaga T, Clouet E, Cluzel M,
Desprez B, Gellatly N, Goebel C, Kern PS, Klaric M, Kühnl J, Lalko JF, Martinozzi-Teissier
S, Mewes K, Miyazawa M, Parakhia R, van Vliet E, Zang Q, Petersohn D.
Non-animal methods to predict skin sensitization (I): the Cosmetics Europe
database. Crit. Rev. Toxicol. 2018, 48 (5): 344-358
Kleinstreuer NC, Hoffmann S, Alépée N, Allen D,
Ashikaga T, Casey W, Clouet E, Cluzel M, Desprez B, Gellatly N, Göbel C, Kern
PS, Klaric M, Kühnl J, Martinozzi-Teissier S, Mewes K, Miyazawa M, Strickland J, van Vliet E, Zang
Q, Petersohn D. Non-animal methods to predict skin sensitization (II): an
assessment of defined approaches. Crit. Rev. Toxicol. 2018, 48 (5): 359-374
van Vliet E, Kühnl J, Goebel C,
Martinozzi-Teissier S, Alépée N, Ashikaga T, Blömeke B, Del Bufalo A, Cluzel M, Corsini E, Delrue N,
Desprez B, Gellatly N, Giese C, Gribaldo L,
Hoffmann S, Klaric M, Maillere B, Naisbitt D, Pallardy M, Vocanson M,
Petersohn D. State-of-the-art and new options to assess T cell activation by skin
sensitizers: Cosmetics Europe Workshop. Altex 2018, 35 (2): 178-192
Klaric M, Bernau M, Duplan H, Eilstein J,
Ellison C, Fabian E, Genies C, Grégoire S, Hewitt N, Jacques-Jamin C, Lester C,
Salhi S, Sorrell I, Schepky A. Cosmetics Europe’s non-animal strategy:
toxicokinetics for systemic toxicity assessment. Oral presentation, GMP
Conference, Paris, France 2018
Kühnl J, Maschmeyer I, Brandmair K, Tao TP,
Gerlach S, Müller-Vieira U, Duplan H, Eilstein J, Ellison C,
Grégoire S; Jacques-Jamin C, Klaric M, Lange D; Lester C, Salhi S, Sorrell I0,
Marx U, Schepky A, Hewitt N. Characterization of chemical metabolism in skin
and liver models over extended and repeated exposure in a multi organ chip
device. Oral presentation, EUSAAT Conference, Linz, Austria 2018
Klaric M, Cubberley R, Sorrell I, Duplan H,
Eilstein J, Ellison C, Grégoire S, Hewitt N, Jacques-Jamin C, Lange D, Lester
C, Rothe H, Salhi S, Schepky A. Evaluation of 6 in silico skin penetration
models to predict the in vitro cutaneous distribution of 25 chemicals. Oral
presentation, Eurotox Conference, Brussels, Belgium 2018
Martina Klaric & Cosmetics Europe Task Force
ADME. In silico modelling of skin penetration. Oral presentation, AlterTox
Meeting, Brussels, Belgium 2018
Schepky A, Cubberley R, Duplan H, Eilstein J,
Ellison C, Grégoire S, Hewitt N, Jacques-Jamin C, Lange D, Roe A, Rothe H,
Salhi S, Klaric M. Cosmetics Europe evaluation of 5 in silico skin penetration models.
Poster, 57th SOT Conference, San Antonio, USA 2018
Obringer C, Tankersley K, Hewitt N, Schepky A,
Lange D, Klaric M, Eilstein J, Grégoire S, Duplan H, Jacques-Jamin C, Cubberley
R, Salhi S, Rothe H, Roe A, Ellison C. Partition and diffusion coefficient determinations
in isolated human skin layers for in silico skin penetration modeling. Poster, 57th
SOT Conference, San Antonio, USA 2018
Efremenko AY, Nicolas CI, Hack E, Ellison C,
Mansouri K, McMullen PD, Klaric M, Hewitt N, Clewell HJ. Evaluation of platforms
used for fit-for-purpose PBPK modeling in chemical safety assessment. Poster,
57th SOT Conference, San Antonio, USA 2018
Ouédraogo G, Van der burg Bart, Bury D, Eilstein
J, Grégoire S, Mahony C, Tozer S, Roe A, Dent M, Nicol B, Cubberley R, Duplan
H, Jacques C, Ellison C, Lange D, Schepky A, Rothe H, Keller D , Hewitt N,
Klaric M, Desprez B. Exposure-led safety assessment framework for systemic
toxicity: initial case studies from Cosmetics Europe. Poster, 57th SOT
Conference, San Antonio, USA 2018
ScitoVation & Cosmetics Europe Task Force
ADME. Incorporating TK data and tools to support regulatory decision making –
from the perspectives of cosmetic industry” OR “Using TK data and tools to
support regulatory decision making – from the perspectives of cosmetic industry.
Poster, Eurotox Conference, Brussels, Belgium 2018
Kühnl J, Maschmeyer I, Brandmair K, Tao TP,
Gerlach S, Müller-Vieira U, Duplan H, Eilstein J, Ellison C, Grégoire S,
Jacques-Jamin C, Klaric M, Lange D; Lester C, Salhi S, Sorrell I, Marx U,
Schepky A, Hewitt N. Characterization of chemical metabolism in a multi organ
chip device integrating skin and liver models. Poster, 20th ESTIV
Conference, Berlin, FRG 2018
Schwarz K, Pappa G, Miertsch H, Scheel J, Koch
W. A methodology for the assessment of inhalation exposure to aluminium from
antiperspirant sprays. Arch. Toxicol. 2018, 92:1383-1392
Steiling W, Almeida JF, Assaf Vandecasteele H,
Gilpin S, Kawamoto T, O’Keeffe L, Pappa G,
Rettinger K, Rothe H, Bowden AM. Principles for the safety evaluation of
cosmetic powders. Toxicol. Lett. 2018, 207: 8-18
Mastrangeli M, Millet S, ORCHID partners (Kuehnl
J), van den Eijnden-van Raaij J. Organ-on-Chip In Development: Towards a
roadmap for Organs-on-Chip. Preprints 2018
2017
Kessler L, Gehrke S, Winnefeld M, Huber B, Hoch E, Walter T, Wyrwa R, Schnabelrauch M, Schmidt M, Kückelhaus M, Lehnhardt M, Hirsch T, Jacobsen F Methacrylated gelatin/hyaluronan-based hydrogels for soft tissue engineering · J Tissue Engin 2017, 21 (8): 1-14
Kuehne A, Hildebrand J, Soehle J, Wenck H, Terstegen L, Gallinat S, Knott A, Winnefeld M, Zamboni N An integrative metabolomics and transcriptomics study to identify metabolic alterations in aged skin of humans in vivo · BMC Genomics 2017, 18 (1): 169
Fiedler J, Grönniger E, Pfanne A, Brönneke S, Schmidt K, Falk CS, Wenck H, Terstegen L, Thum T, Winnefeld M Identification of miR-126 as a new regulator of skin ageing · Exp Dermatol 2017, 26 (3): 284-286
Behm P, Hashemi M, Hoppe S, Wessel S, Hagens R, Jaspers S, Wenck H, Rübhausen M Confocal spectroscopic imaging measurements of depth dependent hydration dynamics of human skin in-vivo. AIP Advances 2017, 7: 115004
Schulze C, Jaspers S Measuring skin cell stiffness. In: Measuring the skin, Agache (ed) · Springer International Publishing AG, Cham, Switzerland 2017: 1511-1521
Mellem D, Sattler M, Pagel-Wolff S, Jaspers S, Wenck H, Rübhausen MA, Fischer F Fragmentation of the mitochondrial network in skin in vivo · PLoS ONE 2017, 12 (6): e0174469
Trautmann M, Wendel V, Prinz D, Primmel B, Willging G, Nagorsen E, Suckert A, Gehm S, Brandt M, Ballay P, Godde B Not only age but also tactile perception influences the preference for cosmetic creams applied to the forearm · Int J Cosmet Sci 2017, 39: 344-350
Peters EMJ, Müller Y, Snaga W, Fliege H, Reißhauer A, Schmidt-Rose T, Max H, Schweiger D, Rose M, Kruse J Hair and stress: A pilot study of hair and cytokine balance alteration in healthy young women under major exam stress · PLoS ONE 2017, 12 (4): e0175904
Traupe B, Fölster H, Max H, Schulz J Effective axillar malodour reduction by polyquaternium-16 containing deodorants · Int J Cosmet Sci 2017, 39: 141-148
Choi W, Jin L, Smuda C, Batzer J, Hearing VJ, Kolbe L Molecular and histological characterization of age spots · Exp Dermatol 2017, 26: 242-248
Ito S, Kolbe L Tyrosine peptides provide a color palette upon tyrosinase oxidation: nanosize does matter · Pigment Cell Melanoma Res 2017, 30 (1): 4-5
Mann T, Gerwat W, Wenck H, Röhm K-H, Kolbe L Isobutylamido thiazolyl resorcinol a new powerful inhibitor of human tyrosinase · Pigment Cell Melanoma Res 2017, 30: e85-e86
Fürtjes T, Weiss KT, Filbry A, Rippke F, Schreml S Impact of a pH5 oil-in-water emulsion on skin surface pH · Skin Pharmacol Physiol 2017, 30: 292-297
Reichert O, Fleming T, Neufang G, Schmelz M, Genth H, Kaever V, Wenck H, Stäb F, Terstegen L, Kolbe L, Roggenkamp D Impaired glyoxalase activity is associated with reduced expression of neurotrophic factors and pro-inflammatory processes in diabetic skin cells · Exp Dermatol 2017, 26 (1): 44-50
Jovanovic Z, Schornstein T, Sutor A, Neufang G, Hagens R Conventional sunscreen application does not lead to sufficient body coverage · Int J Cosmet Sci 2017, 39: 550-55
Ständer S, Blome C, Anastasiadou Z, Zeidler C, Jung KA, Tsianakas A, Neufang G, Augustin M Dynamic pruritus score: Evaluation of the validity and reliability of a new instrument to assess the course of pruritus · Acta Derm Venereol 2017, 97: 230-234
Ständer S, Augustin M, Roggenkamp D, Blome C, Heitkemper T, Worthmann AC, Neufang G Novel TRPM8 agonist cooling compound against chronic itch: results from a randomized, double-blind, controlled, pilot study in dry skin · JEADV 2017, 31: 1064-1068
Meinke M, Richter H, Buerger A, Kohlhase S, Burkhardt T, Rippke F, Patzelt A, Lademann J Follicular penetration of licochalcone A and salicylic acid investigated by differential stripping · Poster P0049, 26th EADV Congress, Geneva 2017
Keyhanian S, Schoelermann AM, Warnke K, Buerger A, Neufang G Beneficial role of adjunctive skin care for patients receiving acne medication · Poster P0057, 26th EADV Congress, Geneva 2017
Keyhanian S, Buerger A , Morgenroth-Ehrich S , Warnke K, Neufang G, Klensang K Efficacy of a new cosmetic formulation containing 10% Hydroxy Complex and licochalcone A in subjects with acne lesions · Poster P0058, 26th EADV Congress, Geneva 2017
Jovanovic Z, Roggenkamp D, Neufang G, Haus A Efficacy and skin tolerability of a skin care regimen with licochalcone A and 4-t-butylcyclohexanol as preparation for and post-treatment of facial erythema with laser · Poster P1305, 26th EADV Congress, Geneva 2017
Krueger A, Filbry A, Mielke H, Gallinat S, Roggenkamp D, Weise J The active ingredient combination of glycine saponin, hyaluronic acid and urea is beneficial for anti-aging efficacy and moisturization in vitro and in vivo · Poster P0490, 26th EADV Congress, Geneva 2017
Jovanovic Z, Sutor A, Hagens R, Schornstein T, Roggenkamp D, Neufang G Common sunscreen application routine does not provide sufficient body coverage · Poster P1623, 26th EADV Congress, Geneva 2017
Welge V, Sulzberger M, Klensang K, Rippke F, Filbry A, Harbig S, Roggenkamp D, Grönniger E The protective shielding effect of a novel body moisturizer for sensitive skin in vitro and in vivo · Poster P1988, 26th EADV Congress, Geneva 2017
Srour J, Bengel J, Linden T, Jovanovic Z, Roggenkamp D, Reinholz M, Rothenberger C, Neufang G, Wollenberg A Skin compatibility and efficacy of a cosmetic skin care regimen with 4-t-butylcyclohexanol in the topical therapy of perioral dermatitis · Poster P2117, 26th EADV Congress, Geneva 2017
Rothe H, Obringer C, Manwaring J, Avci C, Wargniez C, Eilstein J, Hewitt N, Cubberley R, Duplan H, Lange D, Jacques-Jamin C, Klaric M, Schepky A, Gregoire S Comparison of protocols measuring diffusion and partition coefficients in the stratum corneum · J Appl Toxicol 2017, 37: 806-81
Barroso J, Pfannenbecker U, Adriaens E, Alépée N, Cluzel M, De Smedt A, Hibatallah J, Klaric M, Mewes KR, Millet M, Templier M, McNamee P Cosmetics Europe compilation of historical serious eye damage/eye irritation in vivo data analysed by drivers of classification to support the selection of chemicals for development and evaluation of alternative methods/strategies: the Draize eye test Reference Database (DRD) · Arch Toxicol. 2017, 91 (2): 521-54
Schwarz K, Pappa G, Miertsch H, Scheel J, Koch W A methodology for the assessment of inhalation exposure to aluminium from antiperspirant sprays · Arch Toxicol 2017, in press
Jacques-Jamin
C, Duplan H, Rothe H, Vaillant O, Eilstein J, Gregoire S, Cubberley R, Lange D,
Ellison C, Klaric M, Hewitt N, Schepky A
Comparison of the skin penetration
of 3 metabolically stable chemicals using fresh and frozen human skin · Skin
Pharmacol Physiol 2017, 30: 234-245
Schepky A,
Reuter H, Kühnl J, Aeby P Human peripheral blood monocyte derived dendritic cells
assay for the detection and characterization of sensitizers · In: Eskes C, van
Vliet E, Maibach H (eds) Alternatives for dermal toxicity testing Springer,
Cham 2017: 331-345
Van Vliet
E, Kühnl J, Goebel C, Martinozzi-Teissier S, Alepee N, Ashikaga T, Blömeke B,
del Bufalo A, Cluzel M, Corsini E, Delrue N, Desprez B, Gellatly N, Giese C,
Gribaldo L, Hoffmann S, Klaric M, Maillere B, Naisbitt D, Pallardy M, Vocanson
M, Petersohn D
Consensus report: State-of-the-art and new options to
assess T cell activation by skin sensitizers: Cosmetics Europe Workshop · ALTEX
Online first, October 2, 2017
Petry T,
Bury D, Fautz R, Hauser M, Huber B, Markowetz A, Mishra S, Rettinger K, Schuh
W, Teichert T
Review of data on the dermal penetration of mineral oils
and waxes used in cosmetic applications · Toxicol Letters 2017, 280: 70-78
Pfannenbecker
U, Wenck H, Schepky A
Photo-safety assessment for cosmetics based on in vitro tests
·
Toxicol Letters 2017, 280S: S17-S18
Gregoire
S, Cubberley R, Duplan H, Eilstein J, Ellison C, Hewitt N, Jacques-Jamin C,
Lange D, Klaric M, Rothe H, Schepky A, Roe A
Impact of cutaneous bioavailability in local skin
toxicity: Preliminary results from cosmetics Europe skin bioavailability and
metabolism task force · Toxicol Letters 2017, 280S: S44
Grégoire
S, Cubberley R, Duplan H, Eilstein J, Lange D, Hewitt N, Jacques-Jamin C,
Klaric M, Rothe H, Ellison C, Vaillant O, Schepky A
Solvent solubility testing of
cosmetics-relevant chemicals: Methodology and correlation of water solubility
to in silico predictions · J Solution Chem 2017, 46:
1349
Maschmeyer
I, Lorenz A, Bauer S, Ramme A, Rings T, Kuehnl J, Marx U
State-of-the-art of the assessment of ADME using multiple
organs on a chip · Toxicology Letters 2017, 280: S34
Lange D,
Jaques-Jamin C, Eilstein J, Duplan H, Genies C, Gregoire S, Cubberley R,
Ellison C, Klaric M, Roe A, Rothe H, Salhi S, Hewitt N, Schepky A
Comparison of in vitro metabolism models for cosmetics
relevant prediction of skin absorption and toxicity · ALTEX Proc 2017, 6 (1):
24
Schepky A
, Maschmeyer I, Rings T, Huebner J, Gerlach S, Marx U, Kuehnl J
Retinoic acid as an example for a
toxicokinetic study in a multiorgan chip comprising EpiDerm skin models and
liver organoids · ALTEX Proc 2017, 6 (1): 36
Schepky A, Cubberley R, Duplan H, Eilstein J, Ellison C, Gregoire S, Hewitt N, Jaques-Jamin
C, Lange D, Roe A, Rothe H, Klaric M
Better understanding of bioavailability of cosmetic
ingredients: Results from Cosmetics Europe skin bioavailability project · ALTEX
Proc 2017, 6 (1): 39
Alépée N,
Adriaens E, Bagley D, Desprez B, Hibatallah J, Mewes K, Pfannenbecker U, Sala
A, McNamee P
Testing strategies for UN GHS classification for serious
eye damage/eye irritation of chemicals: Cosmetics Europe analysis · ALTEX Proc
2017, 6 (1): 40
Desprez
B, Adriaens E, Alépée N, Bagley D, Hibatallah J, Mewes KR, Pfannenbecker U,
Sala A, McNamee P
The importance of understanding physico-chemical
properties of chemicals in the evaluation of serious eye damage/eye irritation:
Cosmetic Europe analysis · ALTEX Proc 2017, 6 (1): 41
McNamee
P, Alépée N, Adriaens E, Bagley D, Desprez B, Hibatallah J, Mewes K,
Pfannenbecker U, Sala A
Cosmetics Europe eye programme: Relevance to integrated
approaches on testing and assessment for eye hazard ALTEX Proc 2017, 6 (1): 43
Klaric M,
Alépée N, Allen D, Ashikaga T, Casey W, Clouet E, Cluzel M,
Del
Bufalo A, Gellatly N, Goebel C, Hoffmann
S, Kern P, Kleinstreuer N, Kuehnl J, Mewes K, Miyazawa M, Petersohn D,
Strickland J, Van Vliet E, Zang D
Cosmetics Europe assessment of non-animal approaches for
predicting skin sensitization · ALTEX Proc 2017, 6 (1): 94
Desprez
B, Reisinger K, Fieblinger D, Heppenheimer A, Kuehnl J, Kreutz J, Liebsch M,
Luch A, Maul K, Poth A, Strauch P, Voelkner W, Wolf T, Pirow R
The HET-MN (Hen’s Egg Test for Micronucleus-Induction):
Promising pre-validation study · ALTEX Proc 2017, 6 (1):
120
Fautz R,
Desprez B, Hoffmann S, Hewitt N, Fowler P, Reisinger K, Kuehnl J, Ouedraogo G,
Kenny J, Pfuhler S
Use of newly validated 3D reconstructed human skin
genotoxicity assays and hens egg test micronucleus in testing strategies
improve predictions in safety assessments of cosmetic ingredients · ALTEX Proc
2017, 6 (1): 125
292
Desprez
B, Klaric M, Taalman R, Schepky A, Blaauboer B
Cosmetics Europe long range science strategy for
non-animal-based safety assessments · ALTEX Proc 2017, 6 (1): 202
Lange D,
Herberz I, Mikolon J, Akhiani M, Wenck H, Schepky A
Impact of stripping technique in skin penetration studies
on rate of dermal absorption · ALTEX Proc 2017, 6 (1): 225
Mellem D, Sattler M, Pagel-Wolff S, Jaspers S, Wenck
H, Ruebhausen MA, Fischer F. Fragmentation of the mitochondrial network in skin in
vivo. PLoS ONE 2017; 12(6): e0174469.
Clemann
S., Beauty AI: experiments and visions in skin care, lecture on 2nd
Korea Future Forum, Seoul, Korea
Ito
S, Kolbe L. Tyrosine peptides provide a color palette upon tyrosinase
oxidation: nanosize does matter.Pigment Cell Melanoma Res. 2017; 30(1):4-5
Rothe
H, Obringer C, Manwaring J, Avci C, Wargniez W, Eilstein J, Hewitt N, Cubberley
R, Duplan H, Lange D, Jacques-Jamin C, Klaric M, Schepky A, Grégoire S. Comparison
of protocols measuring diffusion and partition coefficients in the stratum
corneum. J Appl Toxicol. 2017; 37(7):806-816
Trautmann
M, Wendel V, Prinz D, Primmel B, Willging G, Nagorsen E, Suckert A, Gehm S,
Brandt M, Ballay P, Godde B. Not only age but also tactile perception influences
the preference for cosmetic creams applied to the forearm. Int J Cosmet Sci.
2017; 39(3):344-350
Peters
EMJ, Müller Y, Snaga W, Fliege H, Reißhauer A, Schmidt-Rose T, Max H, Schweiger
D, Rose M, Kruse J. Hair and stress: A pilot study of hair and cytokine balance
alteration in healthy young women under major exam stress. PLoS ONE. 2017; 12(4):
e0175904
Traupe
B, Fölster H, Max H, Schulz J. Effective axillary malodour reduction by polyquaternium-16-containing
deodorants. Int J Cosmet Sci. 2017; 39(2):141-148
Choi
W, Yin L, Smuda C, Batzer J, Hearing VJ, Kolbe L. Molecular and histological
characterization of age spots. Exp Dermatol. 2017; 26(3):242-248
Fiedler
J, Grönniger E, Pfanne A, Brönneke S, Schmidt K, Falk CS, Wenck H, Terstegen L,
Thum T, Winnefeld M. Identification of miR-126 as a new regulator of skin
ageing. Exp Dermatol. 2017; 26(3):284-286
Kuehne
A, Hildebrand J, Soehle J, Wenck H, Terstegen L, Gallinat S, Knott A, Winnefeld
M, Zamboni N. An integrative metabolomics and transcriptomics study to identify
metabolic alterations in aged skin of humans in vivo. BMC Genomics. 2017; 18(1):169
Barroso
J, Pfannenbecker U, Adriaens E, Alépée N, Cluzel M, De Smedt A, Hibatallah J,
Klaric M, Mewes KR, Millet M, Templier M, McNamee P. Cosmetics Europe
compilation of historical serious eye damage/eye irritation in vivo data analysed
by drivers of classification to support the selection of chemicals for development
and evaluation of alternative methods/strategies: the Draize eye test Reference
Database (DRD). Arch Toxicol. 2017; 91(2):521-547
Reichert
O, Fleming T, Neufang G, Schmelz M, Genth H, Kaever V, Wenck H, Stäb F,
Terstegen L, Kolbe L, Roggenkamp D. Impaired glyoxalase activity is associated with
reduced expression of neurotrophic factors and pro-inflammatory processes in diabetic
skin cells. Exp Dermatol. 2017; 26(1):44-50
Schulze C, Jaspers S. Measuring Skin Cell Stiffness. In:
Measuring the Skin, Agache (ed), Springer International Publishing
AG, Cham, Switzerland pp.1511-1521, 2017
Kuhlmann M, Klensang K, Kristof S, Buck B, Krause-Kyora F, Wolber R, Grönniger E. Determination of the adhesive properties of a first aid dressing with silicone adhesive in comparison to an acrylate-based adhesive. EWMA (European Wound Management Association) Conference, Amsterdam, Netherlands, 2017
2016
Kolbe L. Biological Cell Protection by Natural
Compounds, a Second Line of Defense Against Solar Radiation in:
Skin Stress Reponse Pathways, Wondrak G (ed), Springer International Publishing
AG, Cham, Switzerland, pp 361-378, 2016
Roggenkamp D, Worthmann AC, Sulzberger M, Wenck H,
Stäb F, Neufang G. Menthoxypropanediol inhibits nerve growth factor-induced
nerve fibre sprouting in coculture models of sensory neurons and skin cells.
Exp Dermatol. 2016; 25(10):824-6
Schweiger D, Hoff A, Scheede S, Fischer F, Tilsner J,
Lüttke J, Neumann Y, Hagens R. Towards a body hair atlas of women of caucasian
ethnicity. Int J Cosmet Sci. 2016; 38(4):409-20
Sulzberger M, Fölster H, Sattler M, Rippke F, Grönniger
E. Inhibition of Propionibacterium acnes associated biofilm formation by
Decanediol. J Dermatol Sci.
2016; 83(2):159-61
Huber
B, Link A, Linke K, Gehrke SA, Winnefeld M, Kluger PJ. Integration of Mature
Adipocytes to Build-Up a Functional Three-Layered Full-Skin Equivalent. Tissue
Eng Part C Methods. 2016; 22(8):756-64
Gerstel D, Jacques-Jamin C, Schepky A, Cubberley R,
Eilstein J, Grégoire S, Hewitt N, Klaric M, Rothe H, Duplan H. Comparison of
protocols for measuring cosmetic ingredient distribution in human and pig skin.
Toxicol In Vitro. 2016; 34:153-60
Bormann F, Rodríguez-Paredes M, Hagemann S, Manchanda
H, Kristof B, Gutekunst J, Raddatz G, Haas R, Terstegen L, Wenck H, Kaderali L,
Winnefeld M, Lyko F. Reduced DNA methylation patterning and transcriptional
connectivity define human skin aging. Aging Cell. 2016; 15(3):563-71
Batzer J, Bleckmann A, Lerg H, Schwanke F, Schläger T.
The 'Dispersal Rate' - a product dependent characteristic to predict the
reliability of the calibrated in vitro SPF on WW5 plates. Int J Cosmet Sci.
2016; 38(3):294-304
Alépée N, Hibatallah J, Klaric M, Mewes KR,
Pfannenbecker U, McNamee P. Assessment of cosmetic ingredients in the in vitro
reconstructed human epidermis test method EpiSkin™ using
HPLC/UPLC-spectrophotometry in the MTT-reduction assay. Toxicol In Vitro. 2016;
33:105-17
Kwiatkowski M, Wurlitzer M, Krutilin A, Kiani P, Nimer
R, Omidi M, Mannaa A, Bussmann T, Bartkowiak K, Kruber S, Uschold S, Steffen P,
Lübberstedt J, Küpker N, Petersen H, Knecht R, Hansen NO, Zarrine-Afsar A,
Robertson WD, Miller RJD, Schlüter H. Homogenization of tissues via
picosecond-infrared laser (PIRL) ablation: Giving a closer view on the in-vivo
composition of protein species as compared to mechanical homogenization. J
Proteomics. 2016; 16;134:193-202
Marx U, Andersson TB, Bahinski A, Beilmann M, Beken S,
Cassee FR, Cirit M, Daneshian M, Fitzpatrick S, Frey O, Gaertner C, Giese C,
Griffith L, Hartung T, Heringa MB, Hoeng J, de Jong WH, Kojima H, Kuehnl J,
Leist M, Luch A, Maschmeyer I, Sakharov D, Sips AJ, Steger-Hartmann T, Tagle
DA, Tonevitsky A, Tralau T, Tsyb S, van de Stolpe A, Vandebriel R, Vulto P,
Wang J, Wiest J, Rodenburg M, Roth A: Biology-inspired microphysiological system
approaches to solve the prediction dilemma of substance testing. ALTEX. 2016;
33(3): 272-321.
Roggenkamp D, Koop U, Filbry A, Keyhanian S, de Kleijn
S, Conzelmann S, Neufang G. Vehicle-controlled treatment of xerosis with a
topical formulation containing natural moisturizing factors and lipids. Poster
P2264, 25th EADV Congress, Vienna 2016
Altgilbers S, Holtzmann U, Worthmann A-C, Neufang G,
Rippke F, Grönniger E. The antioxidant Silymarin S protects and activates dermal
microcapillaries in vitro. Poster
P0498, 25th EADV Congress, Vienna 2016
Neufang G, Rümmelein B, Sögding-Beck K, Reljić D,
Demschik G, Rigoni C, Cantú A, Jovanović Z. Dermocosmetic approach in the
management of hypersensitive skin - Results of an international study involving
647 patients. Poster P0490, 25th EADV Congress, Vienna 2016
Van Geloven A, Klensang K, Djamil J, Neufang G, Warnke
K. Formulations containing Silymarin S and Arctiin significantly improve the
elasticity and microvascular structure of ageing skin. Poster P2194, 25th
EADV Congress, Vienna 2016
Bormann F, Rodríguez-Paredes
M, Hagemann S, Manchanda H, Kristof B, Gutekunst J, Raddatz G, Haas R,
Terstegen L, Wenck H, Kaderali L, Winnefeld M, Lyko F. Reduced DNA methylation
patterning and transcriptional connectivity define human skin aging. Aging
Cell. 2016, 15(3): 563-71.
Meinke MC, Schanzer S, Richter H, Rippke F, Filbry A,
Bohnsack K, Patzelt A, Lademann J. Prevention of cutaneous penetration and
CD1c+ uptake of pollen allergens by a barrier-enhancing formulation. Skin
Pharmacol Physiol 2016, 29: 71-75
Klaric M, Pfannenbecker U, Adriaens E, Alepee N,
Barroso J, Hibatallah J, Mewes KR, McNamee P. Critical Review of the UN GHS
Decision Criteria for Chemicals Causing Irreversible Effects on the Eye/Serious
Damage to the Eye: Cosmetics Europe Analysis. 55th Annual Meeting of
the Society of Toxicology, New Orleans 2016 (Poster).
Alépée N, Hibatallah J, Klaric M, Mewes KR,
Pfannenbecker U, McNamee P. Assessment of cosmetic ingredients in the in vitro
reconstructed human epidermis test method EpiSkin™ using
HPLC/UPLC-spectrophotometry in the MTT-reduction assay. Toxicology in Vitro 33,
105–117, 2016.
Darvin ME,
Schanzer S, Lademann J, Tesch M, Buerger A, Rippke F, Meinke MC. Protective efficacy of a licochalcone
A containing sunscreen in the high energy visible spectral range in vivo (abstr.). Exp. Dermatol. 2016,
25: E32
Darvin ME,
Schanzer S, Lademann J, Tesch M, Buerger A, Rippke F, Meinke MC.
Licochalcone A containing sunscreen protects the skin from carotenoid depletion
induced by irradiation with high energy visible light - Results of a
double-blind, vehicle-controlled in vivo
study. Poster P1795, 25th EADV Congress, Vienna 2016
Sulzberger M, Worthmann A-C, Holtzmann U, Buck B, Jung
KA, Schoelermann AM, Rippke F, Stäb F, Wenck H, Neufang G, Grönniger E.
Effective treatment for sensitive skin: 4-t-butylcyclohexanol and licochalcone
A. JEADV 2016, 30 (Suppl. 1): 9-17
Schoelermann AM, Jung KA, Buck B, Groenniger E,
Conzelmann S. Comparison of skin calming effects of cosmetic products
containing 4-t-butylcyclohexanol or acetyl dipeptide-1 cetyl ester on
capsaicin-induced facial stinging in volunteers with sensitive skin. JEADV
2016, 30 (Suppl. 1): 18-20
Schoelermann AM, Weber TM, Arrowitz C, Rize RL, Qian
K, Babcock M. Skin compatibility and efficacy of a cosmetic skin care regimen
with licochalcone A and 4-t-butylcyclohexanol in patients with rosacea subtype
I. JEADV 2016, 30 (Suppl. 1): 21-27
Kuhlmann M, Ekanayake-Bohling S, Klensang K, Hartkopf
C, Saladin S, Wigger-Alberti W. Local tolerability and wound healing properties
of two waterproof dressings for post-operative care after minor surgery.
Congress of the European Wound Management Association, EWMA, Bremen, Germany,
2016 (Poster sub)
Kuhlmann M, Klensang K, Manger C, Saladin S. Local
tolerability, efficacy and acceptability of a corn plaster with salicylic acid
in the treatment of corns. FIP World Congress of Podiatry, 2016 (Poster sub)
Schweiger D, Hoff A, Scheede S, Fischer F, Tilsner J,
Lüttke J, Neumann Y, Hagens R. Towards a Body Hair Atlas of Women of Caucasian
Ethnicity. Int J Cosmet Sci. 38(4): 409-420, 2016
Halm M, Schenke-Layland K, Jaspers S, Wenck H, Fischer
F: Visualizing tropoelastin in a long-term human elastic fibre cell culture
model. Sci Rep. 2016; 6: 20378.
Kwiatkowski M, Wurlitzer M, Krutilin A, Kiani P, Nimer
R, Omidi M, Mannaa A, Bussmann T, Bartkowiak K, Kruber S, Uschold S, Steffen P,
Lübberstedt J, Küpker N, Petersen H, Knecht R, Hansen NO, Zarrine-Afsar A,
Robertson WD, Miller RJ, Schlüter H: Homogenization of tissues via
picosecond-infrared laser (PIRL) ablation: Giving a closer view on the in-vivo
composition of protein species as compared to mechanical homogenization. J
Proteomics. 134: 193-202, 2016.
Mellem D, Fischer F, Jaspers S, Wenck H, Rübhausen M:
Quality Saving Mechanisms of Mitochondria during Aging in a Fully
Time-Dependent Computational Biophysical Model. PLoS ONE. 2016; 11(1): e0146973.
Sieg R, Bautsch J, Ullrich O, Fischer F. Revelations
of Cell Health Through Super-Resolution Imaging of Mitochondrial Networks.
2016, Poster, Studierendentage Hamburg.
