Communications Biology
2022
Interference
and co-existence of staphylococci and Cutibacterium acnes within the healthy
human skin microbiome
Ahle CM, Stødkilde K, Poehlein A, Bömeke M, Streit WR, Wenck H, Reuter JH, Hüpeden J, Brüggemann H.
Frontiers in Genetics
2022
Single-Cell
RNA Profiling of Human Skin Reveals Age-Related Loss of Dermal Sheath Cells
and Their Contribution to a Juvenile Phenotype
Ahlers JMD, Falckenhayn C, Holzscheck N, Solé-Boldo L, Schütz S, Wenck H, Winnefeld M, Lyko F, Grönniger E, Siracusa A.
Regulatory Toxicology and Pharmacology
2022
A
10-step framework for use of read-across (RAX) in next generation risk
assessment (NGRA) for cosmetics safety assessment
Alexander-White C, Bury D, Cronin M, Dent M, Hack E, Hewitt NJ, Kenna G, Naciff J, Ouedraogo G, Schepky A, Mahony C, Europe C.
Skin Pharmacology and Physiology
2022
A
Biomimetic Combination of Actives Enhances Skin Hydration and Barrier
Function via Modulation of Gene Expression: Results of Two Double-Blind,
Vehicle-Controlled Clinical Studies
Altgilbers S, Rippke F, Filbry A, Conzelmann S, Vietzke JP, Burkhardt T, Segger D, Roggenkamp D, Grönniger E.
International Journal of Cosmetic Science
2022
Multidirectional
activity of bakuchiol against cellular mechanisms of facial ageing -
Experimental evidence for a holistic treatment approach
Bluemke A, Ring AP, Immeyer J, Hoff A, Eisenberg T, Gerwat W, Meyer F, Breitkreutz S, Klinger LM, Brandner JM, Sandig G, Seifert M, Segger D, Rippke F, Schweiger D.
Toxicology Research
2022
Assessment
of dermal absorption of aluminium from a representative antiperspirant
formulation using a ((26)Al)Al microtracer approach: a follow-up study in
humans
de Ligt R, Westerhout J, Grossouw D, Buters TP, Rissmann R, Burggraaf J, Windhorst AD, Tozer S, Pappa G, Wall B, Bury D, Mason DR, Vaes WHJ.
NAR Genomics and Bioinformatics
2022
Inter-layer
and inter-subject variability of diurnal gene expression in human skin
Del Olmo M, Spörl F, Korge S, Jürchott K, Felten M, Grudziecki A, de Zeeuw J, Nowozin C, Reuter H, Blatt T, Herzel H, Kunz D, Kramer A, Ananthasubramaniam B.
Skin Research and Technology
2022
Depth-dependent
hydration dynamics in human skin: Vehicle-controlled efficacy assessment of a
functional 10% urea plus NMF moisturizer by near-infrared confocal
spectroscopic imaging (KOSIM IR) and capacitance method complemented by
volunteer perception
Gallinger J, Kuhn A, Wessel S, Behm P, Heinecke S, Filbry A, Hillemann L, Rippke F.
Journal of Investigative Dermatology
2022
Macrophages
Are Polarized toward an Inflammatory Phenotype by their Aged Microenvironment
in the Human Skin
Gather L, Nath N, Falckenhayn C, Oterino-Sogo S, Bosch T, Wenck H, Winnefeld M, Grönniger E, Simm S, Siracusa A.
Journal of Pharmaceutical Sciences
2022
A
Mechanistic Bayesian Inferential Workflow for Estimation of In Vivo Skin
Permeation from In Vitro Measurements
Hamadeh A, Troutman J, Najjar A, Edginton A.
Regulatory Toxicology and Pharmacology
2022
Use of
in vitro metabolism and biokinetics assays to refine predicted in vivo and in
vitro internal exposure to the cosmetic ingredient, phenoxyethanol, for use
in risk assessment
Hewitt NJ, Troutman J, Przibilla J, Schepky A, Ouédraogo G, Mahony C, Kenna G, Varçin M, Dent MP; Cosmetics Europe. Electronic address: cosmeticseurope@cosmeticseurope.eu.
Regulatory Toxicology and Pharmacology
2022
Expansion
of the Cosmetics Europe skin sensitisation database with new substances and
PPRA data
Hoffmann S, Alépée N, Gilmour N, Kern PS, van Vliet E, Boislève F, Bury D, Cloudet E, Klaric M, Kühnl J, Lalko JF, Mewes K, Miyazawa M, Nishida H, Tam Brami MT, Varçin M, Api AM, Europe C.
Journal of the American Academy of Dermatology
2022
Impact
of visible light on skin health: The role of antioxidants and free radical
quenchers in skin protection
Lim HW, Kohli I, Ruvolo E, Kolbe L, Hamzavi IH.
Photochemistry and Photobiology
2022
Mitigating
Visible Light and Long Wavelength UVA1-induced Effects with Topical
Antioxidants
Lyons AB, Zubair R, Kohli I, Nahhas AF, Braunberger TL, Mokhtari M, Ruvolo E, Lim HW, Hamzavi IH.
Frontiers in Molecular Neuroscience
2022
In vitro
models for investigating itch
Mießner H, Seidel J, Smith ESJ.
Archives of Toxicology
2022
Towards
best use and regulatory acceptance of generic physiologically based kinetic
(PBK) models for in vitro-to-in vivo extrapolation (IVIVE) in chemical risk
assessment
Najjar A, Punt A, Wambaugh J, Paini A, Ellison C, Fragki S, Bianchi E, Zhang F, Westerhout J, Mueller D, Li H, Shi Q, Gant TW, Botham P, Bars R, Piersma A, van Ravenzwaay B, Kramer NI.
Frontiers in Pharmacology
2022
Use of
Physiologically-Based Kinetics Modelling to Reliably Predict Internal
Concentrations of the UV Filter, Homosalate, After Repeated Oral and Topical
Application
Najjar A, Schepky A, Krueger CT, Dent M, Cable S, Li H, Grégoire S, Roussel L, Noel-Voisin A, Hewitt NJ, Cardamone E.
Regulatory Toxicology and Pharmacology
2022
Read-across
and new approach methodologies applied in a 10-step framework for cosmetics
safety assessment - A case study with parabens
Ouedraogo G, Alexander-White C, Bury D, Clewell HJ 3rd, Cronin M, Cull T, Dent M, Desprez B, Detroyer A, Ellison C, Giammanco S, Hack E, Hewitt NJ, Kenna G, Klaric M, Kreiling R, Lester C, Mahony C, Mombelli E, Naciff J, O'Brien J, Schepky A, Tozer S, van der Burg B, van Vugt-Lussenburg B, Stuard S, Cosmetics Europe.
Journal of the American Academy of Dermatology
2022
Photoprotection
for all: Current gaps and opportunities
Rigel DS, Lim HW, Draelos ZD, Weber TM, Taylor SC.
International Journal of Cosmetic Science
2022
Evaluation
of efficacy of antioxidant-enriched sunscreen prodcuts against long
wavelength ultraviolet A1 and visible light
Ruvolo E, Boothby-Shoemaker W, Kumar N, Hamzavi IH, Lim HW, Kohli I.
Antioxidants
2022
Assessing
Cellular Uptake of Exogenous Coenzyme Q(10) into Human Skin Cells by X-ray
Fluorescence Imaging
Staufer T, Schulze ML, Schmutzler O, Körnig C, Welge V, Burkhardt T, Vietzke JP, Vogelsang A, Weise JM, Blatt T, Dabrowski O, Falkenberg G, Brückner D, Sanchez-Cano C, Grüner F.
International Journal of Epidemiology
2022
Cohort
Profile Update: The Study of Health in Pomerania (SHIP)
Völzke H, Schössow J, Schmidt CO, Jürgens C, Richter A, Werner A, Werner N, Radke D, Teumer A, Ittermann T, Schauer B, Henck V, Friedrich N, Hannemann A, Winter T, Nauck M, Dörr M, Bahls M, Felix SB, Stubbe B, Ewert R, Frost F, Lerch MM, Grabe HJ, Bülow R, Otto M, Hosten N, Rathmann W, Schminke U, Großjohann R, Tost F, Homuth G, Völker U, Weiss S, Holtfreter S, Bröker BM, Zimmermann K, Kaderali L, Winnefeld M, Kristof B, Berger K, Samietz S, Schwahn C, Holtfreter B, Biffar R, Kindler S, Wittfeld K, Hoffmann W, Kocher T.
Journal of Dermatological Treatment
2022
Exploring
the burden of xerosis cutis and the impact of dermatological skin care from
patient's perspective
von Stülpnagel CC, Augustin M, da Silva N, Schmidt L, Nippel G, Sommer R.