Studies & Publications 1991 – 1995

1995

  • W. Diembeck, V. Schreiner, U. Hoppe: Stratum Corneum Status: Measurement of Electrical Impedance on Excised Pig Skin In Vitro vs. TEWL on Humans In Vivo. Poster, Gordon Research Conference on Barrier Function of Mammalian Skin, Andover, NH, USA (1995)  
  • Arnold, F., Jia, C., He, C., Cherry, G. W., Carbow, B., Meyer-Ingold, W., Bader, D., and West, D. C: Hyaluronan, heterogeneity, and healing: The effects of ultrapure hyaluronan of defined molecular size on the repair of full-thickness pig skin wounds, Wound Rep. Regen. 3, 299 (1995)  
  • Meyer-Ingold, W., and Eichner, W: Platelet-derived growth factor, Cell Biol. Int. 19, 389 (1995)  
  • W. Pape, U. Pfannenbecker, W. Diembeck: A Proposed Strategy for the In Vitro Detection of Phototoxic Agents. Poster, American Academy of Dermatology Meeting, New Orleans (1995)  
  • B.E. Brown, W. Diembeck, U. Hoppe, P.M. Elias: Fate of Topical Hydrocarbons in the Skin. J. Soc. Cosmet. Chem. 46, 1-9 (1995)  
  • Peus, D., Lange, T. S., Wlaschek, M., Meyer-Ingold, W., Ruzicka, T., and Scharffetter-Kochanek, K: Integrin receptor expression in chronic venous leg ulcers, J. Invest. Dermatol. 105, 487 (1995)  
  • Kirchberg, K., Lange, S. T., Klein, E. C., Jungtäubl, H., Heinen, G., Meyer-Ingold, W., and Scharffetter-Kochanek, K: Induction of ß1-integrin synthesis by recombinant platelet-derived growth factor (PDGF-AB) correlates with an enhanced migratory response of human dermal fibroblasts to various extracellular matrix proteins, Exp. Cell Res. 220, 29 (1995)  
  • Peus, D., Jungtäubl, H., Knaub, S., Leuker, A., Gerecht, K., Ostendorf, R., Meyer-Ingold, W., Wlaschek, M., Krieg, T., Ruzicka, T., and Scharffetter-Kochanek, K: Localization of platelet-derived growth factor receptor subunit expression in chronic venous leg ulcers, Wound Rep. Regen. 3, 265 (1995)  
  • H. Beck, F. Benech-Kieffer, P. Courtellemont, W. Diembeck, J. Dupuis, W. Lovell, M. Paye, J. Spengler, W. Steiling: Cosmetic Ingredients: Guideline for Percutaneous Absorption / Penetration. Colipa The European Cosmetic Toiletry and Perfumery Association, Brussels (1995) Colipa Task Force ‘Percutaneous Absorption’  
  • D. Basketter, M. Baverel, W. Diembeck, J. Dupuis, W. Matthies, D. Mougin, M. Paye, R. Röthlisberger, A. Walker: Cosmetic Product Test Guidelines for the Assessment of Human Skin Compatibility. Colipa The European Cosmetic Toiletry and Perfumery Association, Brussels (1995) Colipa Task Force ‘Percutaneous Absorption'  
  • W. Diembeck, W. Pape: Protein (Photo-)Binding Assay. Invittox Protocol No. 111 (ERGATT/FRAME Databank of In Vitro Techniques in Toxicology, ISSN 0960-2194) (1995)  
  • W. Diembeck, W. Pape, U. Pfannenbecker: Entwicklung verträglicher Kosmetika mit Hilfe von in vitro-Tests. Poster, Mitteleurop. Gesellschaft für Alternativen zu Tierversuchen, Linz (1995)  
  • W. Pape, U. Pfannenbecker, W. Diembeck: A Proposed Strategy for the In Vitro Detection of Phototoxic Agents. Poster, COLIPA Scientific Symposium on Alternatives to Animal Testing, Brussels (1995)  
  • R. Fautz, E. Hoting, B. Huber, W. Matthies, W. Pape, G. Schmitt, J. Spengler, W. Sterzel: Implementation of an Animal-free Test Safety Assessment Strategy for Finished Cosmetic  
  • Meyer-Ingold W, Eichner W. Platelet-derived growth factor. Cell Biol Int. 1995 May;19(5):389-98. Review. Products. Poster, COLIPA Scientific Symposium on Alternatives to Animal Testing, Brussels IKW Subgroup ‘Product Safety’ (1995)  
  • A. Walker, D. Basketter, M. Baverel, W. Diembeck, W. Matthies, D. Mougin, M. Paye, R. Röthlisberger, J. Dupuis: COLIPA Test Guideline for the Assessment of Skin Compatibility of Cosmetic Finished Products in Man. Poster, COLIPA Scientific Symposium on Alternatives to Animal Testing, Brussels  COLIPA Task Force ‘Skin Compatibility’ (1995)  
  • W. Pape, H. Spielmann, H. Holzhütter, O. de Silva, J. Dupuis, F. Gerberick, W. Lovell et al.: EU/COLIPA Validation Project on ‘In Vitro Phototoxicity Testing. Poster, COLIPA Scientific Symposium on Alternatives to Animal Testing, Brussels (1995)  
  • H. Beck, F. Benech-Kieffer, P. Courtellemont, W. Diembeck, J. Dupuis, W. Lovell, M. Paye, J. Spengler, W. Steiling: Percutaneous Absorption / Penetration of Cosmetic Ingredients In Vitro. Poster, COLIPA Scientific Symposium on Alternatives to Animal Testing, Brussels Colipa Task Force ‘Percutaneous Absorption’ (1995)  
  • Bagley, F. Baker, M. Bracher, M. Chamberlain, P. Courtellemont, O. de Silva, L. Declercq, L. Earl, S. Freeman, D. Lovell, K. Martin, W. Pape, W. Sterzel, W. Walker: COLIPA In Vitro Eye Irritation Validation Programme. Poster, COLIPA Scientific Symposium on Alternatives to Animal Testing, Brussels Colipa Task Force ‘Methodology Alternatives’ (1995)  
  • Steckel F, Degwert J, Hoppe U. Phenotype and alloactivating capacity of dendritic cells generated under different culture conditions from human peripheral blood. Adv Exp Med Biol. 1995;378:355-7.  
  • F. Steckel, J. Degwert, U. Hoppe: Phenotype and alloactivating capacity of dendritic cells generated under different culture conditions from human peripheral blood  Dendritic Cells in fundamental and Clinical Immunology. Volume 2 Edited by J. Banchereau and D. Schmitt, Plenum Press, New York, 355-357, 1995
  • Degwert J, Steckel F, Hoppe U. Antigen presenting and primary in vitro sensitizing capacity of CD1a+ dendritic cells generated from human blood. Adv Exp Med Biol. 1995;378:187-9.  
  • J. Degwert, F. Steckel, U. Hoppe: Antigen presenting and primary in vitro sensitizing capacity of CDla+ dendritic cells generated from human blood. Dendritic Cells in Fundamental and Clinical Immunology, Volume 2 Edited by J. Banchereau and D. Schmitt, Plenum Press, New York, 187-189, 1995  
  • U. Hoppe, J. Degwert & F. Steckel: Use of cells and keratinocytes to characterize cellular reaction involved in allergic contact dermatitis. Journal of Cellular Biochemistry 21, Suppl, A, 11 (1995)  
  • J. Degwert, F. Steckel & U. Hoppe: Stimulatory capacities of human blood-derived dendritic cells and their phenotypical alterations in the presence of contact sensitizers. Journal of Cellular Biochemistry 21, Suppl. A, 10. (1995)  
  • J. Degwert, F. Steckel, U. Hoppe and L. Kligman: In Vitro Model for Contact Sensitization: Stimulatory Capacities of Human Blood-Derived  Dendritic Cells and Their Phenotypical Alterations in the Presence of Contact Sensitizers. New Trends. In: Allergy IV J. Ring H. Behrendt D.Vieluf (Ed.), Springer-Verlag (1995)
  • Janossy, I.M., Raguz, J.M., Rippke, F., Schwanitz, H.J.: Effekte einer 12,5%igen Nachtkerzensamenöl-Creme auf hautphysiologische Parameter bei atopischer Hautdiathese. Z. Hautkr. 1995, 70 (7): 498-502

1994

  • Pape WJ, Brandt M, Pfannenbecker U. Combined in vitro assay for photohaemolysis and haemoglobin oxidation as part of a phototoxicity test system assessed with various phototoxic substances. Toxicol In Vitro. 1994 Aug;8(4):755-7
  • W. Pape, U. Pfannenbecker, W. Diembeck: A Strategic Approach for In Vitro Phototoxicity Testing. In ‘Alternative Methods in Toxicology. Eds. A. Rougier, A.M. Goldberg, H.I. Maibach  Vol.10: In Vitro Skin Toxicology -- Irritation, Phototoxicity, Sensitisation (1994)  
  • W. Pape, U. Pfannenbecker: RBC Photo Assay - Photohaemolysis and Haemoglobin Oxidation. Invittox Protocol No. 81 (ERGATT/FRAME Databank of In Vitro Techniques in Toxicology, ISSN 0960-2194) (1994)  
  • W. Diembeck, U. Holtzmann: A Rapid and Quantitative Protein Photobinding Assay for the In Vitro Screening of Potential Photoallergens. Poster, IFSCC Congress, Venedig (1994)  
  • U. Kristen , J. P. van Aken , W. Pape , U. Hoppe: The Pollen Tube Growth Test: Use in Eye and Skin Irritancy Assessment. Alternative Methods in Toxicology 10, 69-77, 1994  
  • J. Degwert , W. Pape , U. Hoppe: In vitro analysis of immunoprotective effects of topical sunscreens. Toxic. in Vitro (8) 4, 747-749,  1994  
  • F. Steckel , W. Pape , U. Hoppe: Differentiation of Monocytes in Vitro: Influence of Different Types of Substances. Toxic. in Vitro (8) 4, 743-745 (1994)
  • Schöne, D., Borelli, S., Rippke, F., Marjanovic, N., Philipona, R. Hochwirksame Lichtschutzmittel für Kinder – Stellenwert bei Neurodermitis constitutionalis atopica.Z. Hautkr. 1994, 69 (5): 308-313  
  • Rippke, F., Hölzle, E., Ring, J., Przybilla, B. PUVA-Therapie der Psoriasis –  Prüfmodell und Anwendungsgebiet UV-A-wirksamer medizinischer Lichtschutzmittel.Z. Hautkr. 1994, 69 (10): 671-676

1993

  • Korsch, E., Weltersbach, W., Welters, K., Rippke, F., Bläker, F.: Therapie mit Nachtkerzensamenöl-Kapseln bei schwerem atopischem Ekzem. Sozialpäd. 1993, 1: 12-17 
  • Rippke, F.: Lichtschutz im Kindesalter – ein Beratungsthema von wachsender Bedeutung. MGDA-Dialog 1993, 2: 27-29  
  • W. Pape; J. Degwert; F. Steckel; U. Hoppe: Immunocompetent cells for in vitro screening of skin irritation. Toxic. in Vitro 7, (4), 389-392, (1993)  
  • W. Pape, M. Brandt, U. Pfannenbecker: Combined in vitro assay for photohaemolysis and Hb-oxidation as part of a phototoxicity test system examined on twelve phototoxicants. Poster, Congress on Practical In Vitro Toxicology III, Nottingham UK (1993)  
  • W. Pape, M. Brandt, U. Pfannenbecker: Combined in vitro assay for photohaemolysis and Hb-oxidation as part of a phototoxicity test system examined on twelve phototoxicants. Toxicology In Vitro, 8 (1993)  
  • W. Pape, M. Brandt, U. Pfannenbecker: Combined in vitro assay for photohaemolysis and Hb-oxidation as part of a phototoxicity test system examined on twelve phototoxicants. Poster, First World Congress on Alternatives, Baltimore USA (1993)  
  • H. Spielmann, M. Balls, B. Döring, H.G. Holzhütter, S. Kalweit, G. Klecak, H. L’Eplattenier, M. Liebsch, W. Lovell, T. Maurer, F. Moldenhauer, L. Moore, W. Pape, U. Pfannenbecker, J. Potthast, O. de Silva, W. Steiling, A. Willshaw: EEC / Colipa project on in vitro phototoxicity testing: first results obtained with a Balb/c 3T3 cell phototoxicity assay. Poster, Congress on Practical In Vitro Toxicology III, Nottingham UK (1993)  
  • Meyer-Ingold, W: Wound therapy: Growth factors as agents to promote healing, Trends Biotechnol. 11, 387 (1993)  
  • H. Spielmann, M. Balls, B. Döring, H.G. Holzhütter, S. Kalweit, G. Klecak, H. L’Eplattenier, M. Liebsch, W. Lovell, T. Maurer, F. Moldenhauer, L. Moore, W. Pape, U. Pfannenbecker, J. Potthast, O. de Silva, W. Steiling, A. Willshaw:  EEC / Colipa project on in vitro phototoxicity testing: first results obtained with a Balb/c 3T3 cell phototoxicity assay. Toxicology In Vitro, 8 (1993)  
  • U. Kristen, U. Hoppe, W. Pape: The Pollen Tube Growth Test: A New Alternative to the Draize Eye Irritation Assay. J. Soc. Cosmet. Chem. 44, 153-62 (1993)
  • Kristen, U. Hoppe, W. Pape: The Pollen Tube Growth Test: A New Alternative to the Draize Eye Irritation Assay. Poster, American Academy of Dermatology Meeting, Washington D.C. (1993)

1992

  • G SAUERMANN, A HERPENS, D DREWES, A GRIMMERT, B AUGUST, U HOPPE: Fluorescence-free UV/VIS reflection spectra of human skin. Journal of the Society of Cosmetic Chemists, 1992  
  • W. Pape: Red Blood Cell Test System Invittox Protocol No. 37 (ERGATT/FRAME Databank of In Vitro Techniques in Toxicology. ISSN 0960-2194) (1992)
  • Scharffetter-Kochanek, K., Knaub, S., Jungtäubl, H., Kirchberg, K., Heinen, G., Meyer-Ingold, W., Goerz, G., and Wlaschek, M: “Epidermo-dermal interactions during wound healing“ Zentralblatt Haut- und Geschlechtskrankheiten 161, 250 (1992)

1991

  • W. Pape, U. Hoppe: Standardisation on an in vitro red blood cell test for evaluating the acute cytotoxic potential of tensides. Drug Research, 40 (1991)  
  • W. Pape, U. Hoppe: In vitro methods for the assessment of primary local effects of topically applied preparations. Skin Pharmacology, Vol. 4 (1991)  
  • Lechner, W., Schulmeyer, M., Rippke, F.: Lichtschutz bei atopischer DermatitisTW Dermatologie 1991, 21 (7): 493-500